Thursday, March 9, 2017

Dementia linked to Autoimmune Illnesses? This is both interesting and frightening....


Dementia Risk Up with Autoimmunity



http://www.medpagetoday.com/rheumatology/generalrheumatology/63498?xid=nl_mpt_special_reports_2017-03-09%20&uun=g773630d0r5952786u


Here are a few excerpts from the article on Medpage Today...

Among the 25 autoimmune diseases, 18 had significant positive associations for dementia (P for all <0 .001="" p="">
  • Addison's disease, RR 1.48 (95% CI 1.34-1.64)
  • Multiple sclerosis, RR 1.97 (95% CI 1.88-2.07)
  • Psoriasis, RR 1.29 (95% CI 1.25-1.34)
  • Systemic lupus erythematosus, RR 1.46 (95% CI 1.32-1.61)
  • Thyrotoxicosis, RR 1.31 (95% CI 1.27-1.34)

Of the 81,502 patients with autoimmune disease who also developed dementia, the subtype of dementia was identified in 42,568 -- 20,032 with Alzheimer's and 22,536 with vascular dementia.


Risks for vascular dementia but not Alzheimer's disease were increased for idiopathic thrombocytopenia purpura, pemphigus, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, and most notably, for polyarteritis nodosa, with a rate ratio of 2.12 (95% CI 1.42-3.05, P<0 .001="" p="">
I have a "genetic" factor for autoimmune illnesses on my Mom's side... and also Dementia and Alzheimer's on my maternal side... Cause to really be upsetting and hope they do much more research into this....

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